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Recombinant Rat cAMP-dependent protein kinase type II-alpha regulatory subunit (Prkar2a)

Recombinant Rat cAMP-dependent protein kinase type II-alpha regulatory subunit (Prkar2a)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Prkar2a

Uniprot NO.

P12368

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

2-401

Target Protein Sequence

SHIQIPPGL TELLQGYTVE VLRQQPPDLV DFAVEYFTRL REARRQESDS FIAPPTTFHA QESSGVPVIE EDGESESDSD DEDLEVPIPS KFTRRVSVCA ETFNPDEEED NDPRVVHPKT DEQRYRLQEA CKDILLFKNL DQEQLSQVLD AMFEKIVKTD EHVIDQGDDG DNFYVIERGT YDILVTKDNQ TRSVGQYDNR GSFGELALMY NTPRAATIVA TSDGSLWGLD RVTFRRIIVK NNAKKRKMFE SFIESVPLFK SLEMSERMKI VDVIGEKIYK DGERIITQGE KADSFYIIES GEVSILIRSK TKTNKNGGNQ EVEIAHCHKG QYFGELALVT NKPRAASAYA VGDVKCLVMD VQAFERLLGP CMDIMKRNIS HYEEQLVKMF GSNLDLLDPG Q
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Gene References into Functions

The crystal structure of the helical motif from D-AKAP2 (Akap10), a dual-specific AKAP, bound to the RIIalpha D/D domain from Prkar2a, was analysed. PMID:17081990

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Subcellular Location

Cytoplasm. Cell membrane.

Protein Families

CAMP-dependent kinase regulatory chain family

Tissue Specificity

Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Database Links

UNIGENE: Rn.9742

KEGG: rno:29699

STRING: 10116.ENSRNOP00000027552

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