Recombinant Rat Wnt inhibitory factor 1 (Wif1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Wif1

Purity

>85% (SDS-PAGE)

Target Names

Wif1

Uniprot NO.

Q6IN38

Alternative Names

Wif1Wnt inhibitory factor 1; WIF-1

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

29-379

Target Protein Sequence

GQ PPEESLYLWI DAHQARVLIG FEEDILIVSE GKMAPFTHDF RKAQQRMPAI PVNIHSMNFT WQASGQAEYF YEFLSLRSLD KGIMADPTVN VPRLGTVPHK ASVVQVGFPC LGKQDGVAAF EVNVIVMNSE GNPILRTPQN AIFFKTCQQA ECPGGCRNGG FCNERRVCEC PDGFYGPHCE KALCIPRCMN GGLCVTPGFC ICPPGFYGVN CDKANCSATC FNGGTCFYPG KCICPPGLEG EQCELSKCPQ PCRNGGKCIG KSKCKCPKGY QGDLCSKPVC EPGCGAHGTC HEPNKCQCRE GWHGRHCNKR YGASLMHAPR PAGAGLERHT PSLKKAEGRR DPPESNYIW
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.

Gene References into Functions

Data show that microRNA miR-17-5p over-expression promoted the activation of hepatic stellate cell (HSC) and contributed to the reduction of Wnt inhibitory factor 1 (WIF1) levels. PMID:26637809
GLT mRNA was translated in Wnt-1-expressing C6 cells when the GLT mRNA required no splicing before translation occurred PMID:12470708
Wif-1 inhibits proliferation of neoplastic choroid plexus epithelial cells PMID:19621428

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Subcellular Location

Secreted.

Database Links

UNIGENE: Rn.74256

KEGG: rno:114557

STRING: 10116.ENSRNOP00000006426

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