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Recombinant Rat Secreted frizzled-related protein 1 (Sfrp1)

Recombinant Rat Secreted frizzled-related protein 1 (Sfrp1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Sfrp1

Purity

>85% (SDS-PAGE)

Target Names

Sfrp1

Uniprot NO.

Q9R168

Alternative Names

Sfrp1; Secreted frizzled-related protein 1; sFRP-1; Fragment

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-158

Target Protein Sequence

VRDSCEPVMQ FFGFYWPEML KCDKFPEGDV CIAMTPPNAT EASKPQGTTV CPPCDNELKS EAIIEHLCAS EFALRMKIKE VKKENGDKKI VPKKKKPLKL GPIKKKELKR LVLFLKNGAD CPCHQLDNLS HNFLIMGRKV KSQYLLTAIH KWDKKNKE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels. Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

Subcellular Location

Secreted.

Protein Families

Secreted frizzled-related protein (sFRP) family

Database Links

UNIGENE: Rn.163333

STRING: 10116.ENSRNOP00000024128

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