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Recombinant Rat Receptor-type tyrosine-protein phosphatase R (Ptprr), partial

Recombinant Rat Receptor-type tyrosine-protein phosphatase R (Ptprr), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Ptprr

Uniprot NO.

O08617

Alternative Names

Ptprr; Ptp; Receptor-type tyrosine-protein phosphatase R; R-PTP-R; PC12-PTP1; Protein-tyrosine phosphatase PCPTP1; Tyrosine phosphatase CBPTP

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.

Subcellular Location

[Isoform 3]: Cytoplasm.; [Isoform 2]: Cytoplasm.; [Isoform 1]: Cytoplasm.; [Isoform 4]: Cell membrane; Single-pass type I membrane protein.

Protein Families

Protein-tyrosine phosphatase family, Receptor class 7 subfamily

Tissue Specificity

Widely expressed in the brain, most abundant in cerebellum, midbrain, cerebral cortex and hippocampus. Also expressed in heart and skeletal muscle.

Database Links

UNIGENE: Rn.6277

KEGG: rno:94202

STRING: 10116.ENSRNOP00000006401

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