Recombinant Rat Protein Mdm4 (Mdm4)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Mdm4

Purity

>85% (SDS-PAGE)

Target Names

Mdm4

Uniprot NO.

Q5XIN1

Alternative Names

Mdm4; Mdmx; Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-490

Target Protein Sequence

MTSHSTSAQC SASDSACRIS SEQINQQVRP KLQLLKILQA AGAQGEVFTM KEVMHYLGQY IMVKQLYDQQ EQHLVYCGGD LLGDLLGCQS FSVKDPSPLY DMLRKNLVTS ASVNTDAAQT LALAQDHTMD IPSQDRLKHG ATECSNPRKR TEEDDTHTLP TSRRKCRDSR ADEDLIEHLS QDETSRLDLD FEEWDVAGLP WWFLGNLRNN YIPRSNGSTD LQTNQDIGTA IVSDTTDDLW FLNETVSEQL GVGVKVEAAN CEQPSEVGRT RDKKMVEGGK DDDLEDSKSL SDDTDVEVTS EDEWQCTECK KFNSPSKRYC FRCWALRKDW YSDCSKLTHS LSTSNITAIP EKKDNEGIDV PDCRRTISAP VVRPKDGYLK EEKPRFDPCN SVEFLDLAHG SESQEIISST REQTDIFSEQ KTETESMEDF QNVLKPCSLC EKRPRDGNII HGKTSHLTTC FHCARRLKKS GASCPACKKE IQLVIKVFIA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.

Subcellular Location

Nucleus.

Protein Families

MDM2/MDM4 family

Database Links

UNIGENE: Rn.146603

KEGG: rno:304798

STRING: 10116.ENSRNOP00000012984

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