Recombinant Rat Prominin-2 (Prom2), partial

Code
MSDS	MSDS
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Product Details

Purity

>85% (SDS-PAGE)

Target Names

Prom2

Uniprot NO.

Q8CJ52

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Description

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Target Background

Gene References into Functions

Study shows that prominin-2 prevents the formation of caveolae in normal and ovarian hyperstimulated pregnancy. PMID:29113580
results argue that PROML2 is a novel proapoptotic membrane protein; its down-regulation may associate with aggressive phenotype of prostate cancer cells PMID:12446606
These data show that all the characteristics of prominin-1 are shared by prominin-2, which is in agreement with a possible redundancy in their role as potential organizers of plasma membrane protrusions. PMID:17109118

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Subcellular Location

Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the apical and basolateral membranes of epithelial cells. Associates with membrane in a cholesterol-dependent manner. Colocalizes with PROM1.

Protein Families

Prominin family

Tissue Specificity

In the ventral prostate, expressed in glandular epithelial cells.

Database Links

UNIGENE: Rn.82155

KEGG: rno:192211

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