Recombinant Rat Pituitary homeobox 2 (Pitx2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

Pitx2

Purity

>85% (SDS-PAGE)

Target Names

Pitx2

Uniprot NO.

Q9R0W1

Alternative Names

Pitx2; Ptx2; Pituitary homeobox 2; Homeobox protein PITX2; Paired-like homeodomain transcription factor 2; rPtx2

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-324

Target Protein Sequence

MNCMKGPLPL EHRAAGTKLS AASSPFCHHT QALAMASVLA PGQPRSLDAS KHRLEVHTIS DTSSPEVAEK DKGQQGKNED VGAEDPSKKK RQRRQRTHFT SQQLQELEAT FQRNRYPDMS TREEIAVWTN LTEARVRVWF KNRRAKWRKR ERNQQAELCK NGFGPQFNGL MQPYDDMYPG YSYNNWAAKG LTSASLSTKS FPFFNSMNVN PLSSQSMFSP PNSISSMSMS SSMVPSAVTG VPGSSLNSLN NLNNLSSPSL NSAVPTPACP YAPPTPPYVY RDTCNSSLAS LRLKAKQHSS FGYASVQNPA SNLSACQYAV DRPV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach.

Gene References into Functions

The present study suggests the presence of age-dependent left atrial Pitx2 down-regulation in SHRs PMID:24908044
Data suggest that up-regulation of Pitx2 expression induces decrease in cell proliferation associated with an accumulation of neural stem cells in G1 phase; Pitx2 expression causes up-regulation in expression of cell cycle inhibitor p21 (Cdkn1a). PMID:23131154
the paired-like homeobox transcription factors Pitx1 and Pitx2 are factors functionally activating the proximal human prolactin promoter (hPRL-164luc) PMID:12223489
The present study reveals that the reduced Pitx2 expression in hypothyroid ovary could lead to ovarian dysfunction by modulating the Pitx2-Plod2 interaction. PMID:17982271