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Recombinant Rat Natural cytotoxicity triggering receptor 1 (Ncr1), partial

Recombinant Rat Natural cytotoxicity triggering receptor 1 (Ncr1), partial

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Source
Conjugate
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Product Details

Abbreviation

Ncr1

Purity

>85% (SDS-PAGE)

Target Names

Ncr1

Uniprot NO.

Q9Z0H5

Alternative Names

Ncr1; Ar1; Kilr1; Ly94; Natural cytotoxicity triggering receptor 1; Activating receptor 1; rAR-1; Lymphocyte antigen 94 homolog; NK receptor KILR-1; NKACTR; Natural killer cell p46-related protein; NK-p46; NKp46; CD antigen CD335

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Gene References into Functions

Dendritic cells and hepatoma cell line McA stimulate interferon-gamma production from natural killer (NK) cells in a cell-cell contact-dependent manner via different NK-activating receptors, NKp46 and NKp30, respectively. PMID:21106845
NKp46 activates natural killer cell cytotoxicity by similar pathways as CD16. PMID:15356098

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Subcellular Location

Cell membrane; Single-pass type I membrane protein.

Protein Families

Natural cytotoxicity receptor (NCR) family

Tissue Specificity

Weakly expressed in spleen, heart and lung.

Database Links

UNIGENE: Rn.30049

KEGG: rno:117547

STRING: 10116.ENSRNOP00000025080

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