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Recombinant Rat Muellerian-inhibiting factor (Amh), partial

Recombinant Rat Muellerian-inhibiting factor (Amh), partial

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Amh

Uniprot NO.

P49000

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Gene References into Functions

The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID:27030385
AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID:26753790
Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID:25667201
AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID:21637711
In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID:20816688
Mullerian inhibiting substance regulates gonadotropin gene expression PMID:12878721
MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID:14585814