Recombinant Rat Meteorin (Metrn)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Metrn

Purity

>85% (SDS-PAGE)

Target Names

Metrn

Uniprot NO.

Q5Q0T9

Alternative Names

Metrn; HyracMeteorin; Hypoxia/reoxygenation regulatory factor

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

22-291

Target Protein Sequence

GYSEDRCSW RGSGLTQEPG SVGQLTLDCT EGAIEWLYPA GALRLTLGGS DPGTRPSIVC LRPTRPFAGA QVFAERMAGN LELLLAEGQG LAGGRCMRWG PRERRALFLQ ATPHRDISRR VAAFQFELHE DQRAEMSPQA QGFGVDGACR PCSDAELLLT ACTSDFVIHG TIHGVVHDME LQESVITVVA TRVIRQTLPL FQEGSSEGRG QASVRTLLRC GVRPGPGSFL FMGWSRFGEA WLGCAPRFQE FSRVYSAALA AHLNPCEVAL D
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.

Gene References into Functions

Metrn promotes migration of neuroblasts from subventricular zone explants of postnatal rats and stroke-subjected adult rats via a chemokinetic mechanism. PMID:22044868
Cellular protection afforded by meteorin is associated with normalization of neurological performance on spontaneous forelimb placing and cylinder behavioral tests. PMID:20840868
Data show that Meteorin is expressed in the central nervous system both during development and in adult mice. PMID:19259827

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Subcellular Location

Secreted.

Protein Families

Meteorin family

Database Links

UNIGENE: Rn.50391

KEGG: rno:287151

STRING: 10116.ENSRNOP00000026676

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