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Recombinant Rat Leukemia inhibitory factor receptor (Lifr), partial

Recombinant Rat Leukemia inhibitory factor receptor (Lifr), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Lifr

Uniprot NO.

O70535

Alternative Names

LifrLeukemia inhibitory factor receptor; LIF receptor; LIF-R; CD antigen CD118

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

Gene References into Functions

LIF and its subunit receptor LIFRalpha are constitutively expressed during fetal lung development and that they have an inhibitory physiological role on fetal lung branching. PMID:22291973
continuous orthodontic forces induce the upregulation of production, suggesting that LIFR may play important role in periodontium remodeling PMID:21446866
LIFR signaling can exert negative regulatory effects on neurite extension and branching of sympathetic neurons PMID:12871977
Leukemia inhibitory factor receptor and gp130 were expressed in neurons, and the ischemic damage of these proteins was rescued in the high-LIF group PMID:15716858
tumor necrosis factor alpha (TNF) regulates the expression of the leukemia inhibitor factor receptor (LIFR) gp190 in RBE4 cells PMID:17873291