Recombinant Rat Lamin-B1 (Lmnb1)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Lmnb1

Uniprot NO.

P70615

Alternative Names

Lmnb1; Lamin-B1

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

2-584

Target Protein Sequence

ATATPVQQR AGSRASAPAT PFSPTRLSRL QEKEELRELN DRLAVYIDKV RSLETENSAL QLQVTEREEV RGRELTGLKA LYETELADAR RALDDTARER AKLQIELGKF KAEHDQLLLN YAKKESDLSG AQIKLREYEA ALNSKDAALA TALGDKKSLE GDLEDLKDQI AQLEASLSAA KKQLADETLL KVDLENRCQS LTEDLEFRKN MYEEEINETR RKHETRLVEV DSGRQIEYEY KLAQALHEMR EQHDAQVRLY KEELEQTYHA KLENARLSSE MNTSTVNSAR GGMMESRMRI ESLSSQLSNL QKDSRACLER IQELEDMLAK ERDNSRRMLS DKEREMAEIR DQMQQQLNDY EQLLDVKLAL DMEISAYRKL LEGEEERLKL SPSPSSRVTV SRASSSRSVR TTRGKRKRVD VEESEASSSV SISHSASATG NVCIEEIDVD GKFIRLKNTS EQDQPMGGWE MIRKIGDTSV SYKYTSRYVL KAGQTVTVWA ANAGVTASPP TDLIWKNQNS WGTGEDVKVV LKNSQGEEVA QRSTVFKTTI PEEEEEEEEE PIGVPLEEER FHQQGTPRAS NKSC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.

Gene References into Functions

This differential expression pattern of lamin b1 in retinal neurons suggests that they may be involved in cellular differentiation and expression of cell-specific genes in individual retinal neurons. PMID:21842415

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Subcellular Location

Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.

Protein Families

Intermediate filament family

Database Links

UNIGENE: Rn.11362

KEGG: rno:116685

STRING: 10116.ENSRNOP00000019351

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