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Recombinant Rat Intermediate conductance calcium-activated potassium channel protein 4 (Kcnn4), partial

Recombinant Rat Intermediate conductance calcium-activated potassium channel protein 4 (Kcnn4), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Kcnn4

Purity

>85% (SDS-PAGE)

Target Names

Kcnn4

Uniprot NO.

Q9QYW1

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin.

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

Potassium channel KCNN family, KCa3.1/KCNN4 subfamily

Database Links

UNIGENE: Rn.44212

STRING: 10116.ENSRNOP00000026489

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