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Recombinant Rat Interleukin-1 receptor-associated kinase-like 2 (Irak2)

Recombinant Rat Interleukin-1 receptor-associated kinase-like 2 (Irak2)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Irak2

Purity

>85% (SDS-PAGE)

Target Names

Irak2

Uniprot NO.

Q4QQS0

Alternative Names

Irak2Interleukin-1 receptor-associated kinase-like 2; IRAK-2

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-624

Target Protein Sequence

MACYIYQLPS WVLDDLCRNI DTLSEWDWMQ FASYVITDLT QLRKIKSMER VQGVSITREL LWWWSMRQAT VQQLVDLLCH LELYRAAQIV LSWKPAPDSL SPLSAFPEAV KPGPVATSGR NLKDDQKKGQ PVKPCSFLSS GTTMAGAQQQ ASCQRPCEED APCSLKTDVP DSLQSKYCST SIPKQEKLLN LPGDRLFWSE ADIVQATEDF DQSHRISEGT FADIYRGQRN GVAFAFKRLR EVTGSSPGSM DRFLQAEMQL CLRCCHPNIL PLLGFCTGRQ FHSLIYPYMA NGSLQDRLWA QGDSDMLSWP QRASICSGLL LAVEHLHSLD IIHSNVKSAN VLLDQHLNPK LAHPVAHPCP TNKKTKYTVM KTHLFQASAA YLPENFIRVG QLTKQVDIFS CGIVLAEVLT GIPAMDKDRS PVYLKDLLLS EIPSNTSSVH SRKTSMGKVV VKEICQKHLE RKAGLLPEAC AETWATAVSV CLRRREASLE EARVSMAGVE EQLRGQLSLP WSRVSEDTGS SSNTPEETDD VDNSSLSVPS SVMVVSCARV SSPPPSMGNG TAQPSTSGRQ EADSSSEACA GPQPPQEATE TSWKIEINEA KRRLMENILL YKEEKLDSVE LFGP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Gene References into Functions

Elevated circulating IL-1beta contributed to promote ER stress- induced myocytes apoptosis by affecting IRAK-2/CHOP pathway in diabetic cardiomyopathy. PMID:26394923
Expression of Irak2 increases ~ 15-fold at night in the rat pineal gland, as a result of adrenergic-cyclic AMP signalling. Night time levels are >15-fold greater than median expression levels in other tissues. PMID:19103603

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Protein Families

Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily

Database Links

UNIGENE: Rn.17123

KEGG: rno:362418

STRING: 10116.ENSRNOP00000034508

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