Recombinant Rat Integrin alpha-D (Itgad), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Itgad

Purity

>85% (SDS-PAGE)

Target Names

Itgad

Uniprot NO.

Q9QYE7

Alternative Names

Itgad; Itgax; Integrin alpha-D; CD antigen CD11d

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood.

Gene References into Functions

Recovery from Antiglomerular Basement Membrane Glomerulonephritis Is Associated with Glomeruli-Infiltrating CD8alpha+CD11c+MHC Class II+ Cells PMID:22068125
An anti-CD11d monoclonal antibody improves motor performance, reduces pain and histopathological damage in animals following clip-compression injury. PMID:21145887
CD11d expression increased in retroperitoneal white adipose tissue of Zucker obese rats. PMID:21508205

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Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Families

Integrin alpha chain family

Database Links

UNIGENE: Rn.34728

KEGG: rno:64350

STRING: 10116.ENSRNOP00000026855

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