Recombinant Rat Inhibin beta C chain (Inhbc)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Abbreviation

Inhbc

Purity

>85% (SDS-PAGE)

Target Names

Inhbc

Uniprot NO.

Q9WUK5

Alternative Names

Inhbc; Inhibin beta C chain; Activin beta-C chain

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

237-351

Target Protein Sequence

INCQ GLSRMCCRQE FFVDFREIGW HDWIIQPEGY AMNFCTGQCP LHVAGMPGIS ASFHTAVLNL LKANTDAGTA RRGSCCVPTS RRPLSLLYYD RDSNIVKTDI PDMVVEACGC S
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Gene References into Functions

Expression and dimerization of the rat activin subunits betaC and betaE: evidence for the ormation of novel activin dimers. PMID:11932210
first report of a biological activity of activin C and E supports an involvement in liver tissue homeostasis PMID:12865331
These results indicate that liver regeneration is accelerated in activin betaC-overexpressing liver, and that betaC may function to promote replication of hepatocytes during liver regeneration. PMID:16085335

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Subcellular Location

Secreted.

Protein Families

TGF-beta family

Database Links

UNIGENE: Rn.48697

KEGG: rno:64549

STRING: 10116.ENSRNOP00000010240

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