Recombinant Rat Glutamyl aminopeptidase (Enpep), partial

Product Details

Purity
>85% (SDS-PAGE)
Target Names
Enpep
Uniprot NO.
Alternative Names
EnpepGlutamyl aminopeptidase; EAP; EC 3.4.11.7; Aminopeptidase A; AP-A; CD antigen CD249
Species
Rattus norvegicus (Rat)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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 Customer Reviews

Target Background

Function(From Uniprot)
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
Gene References into Functions
  1. A discrepancy between the high expression of AP-A in kidney of hyperthyroid rats and the low activity of AP-A measured in plasma and kidney of hyperthyroid animals was found. PMID:25960007
  2. Hypertension caused by chronic ethanol treatment as well as L-NAME administration could be associated with the reduction of aminopeptidase N and aminopeptidase A activity. PMID:17519555

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Subcellular Location
Cell membrane; Single-pass type II membrane protein.
Protein Families
Peptidase M1 family
Tissue Specificity
Highest expression in kidney proximal tubules and ileum enterocytes. High expression also detected in liver and pituitary. Lower levels in heart, adrenal gland and brain. Not detected in aorta, lung or spleen. In heart, higher levels in ventricle than in
Database Links
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