Recombinant Rat Glandular kallikrein-7, submandibular/renal (Klk7)

Code
MSDS
Size Pls inquire
Source
Conjugate
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Klk7
Uniprot NO.
Alternative Names
Klk7; Klk-7; Glandular kallikrein-7; submandibular/renal; rGK-7; EC 3.4.21.35; Esterase B; Kallikrein-related protein K1; Proteinase A; RSKG-7; Tissue kallikrein
Species
Rattus norvegicus (Rat)
Source
Yeast
Expression Region
25-261
Target Protein Sequence
VIGGYK CEKNSQPWQV ALYSFTKYLC GGVLIDPSWV ITAAHCSSNN YQVWLGRNNL LEDEPFAQHR LVSQSFPHPD YKPFLMRNHT RKPGDDHSND LMLLHLSQPA DITDGVKVID LPTEEPKVGS TCLASGWGST KPLIWEFPDD LQCVNIHLLS NEKCIKAYKE KVTDLMLCAG ELEGGKDTCT GDSGGPLLCD GVLQGITSWG SVPCAKTNMP AIYTKLIKFT SWIKEVMKEN P
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney.
Gene References into Functions
  1. Tissue kallikrein 1 and TIMP1 expressed in a coexpression vector synergistically inhibited the proliferation of rat vascular smooth muscle cells. PMID:26252163
  2. Gonadectomy influences blood pressure through the kallikrein-kinin system. PMID:19816038
  3. Klk7 rat gene was expressed at high levels in the submandibular glands of transgenic mice. PMID:17366701
  4. Kal7 plays an essential role in synaptic structure and function, affecting a subset of cognitive processes. PMID:19020030
  5. Plasma kallikrein levels are increased in the retina of rats with Ang II-stimulated hypertension. PMID:19124682

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Protein Families
Peptidase S1 family, Kallikrein subfamily
Tissue Specificity
Kidney and submandibular gland. Not expressed in liver, pancreas, spleen, parotid, testis, cortex, prostate, ovary and pituitary.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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