Recombinant Rat Fibroblast growth factor 10 (Fgf10)

1. Direct delivery of fibroblast growth factor-10 (FGF-10) in the lungs of rats led to an increase of lung-resident mesenchymal stem cells (LR-MSCs) in the treated lungs, suggesting that the protective effect of FGF-10 might be mediated, in part, by the mobilization of LR-MSCs in lungs. PMID:26869337
2. Suggest the potential involvement of altered Fgf10/Fgfr2/AR signaling in pathogenesis of anorectal malformations induced by di-n-butyl phthalate. PMID:26514922
3. FGF10 is involved in fetal lung fluid secretion and lung branching. PMID:23143078
4. FGF-10 effects on lung branching morphogenesis are heparin-dependent.FGF-10 may also function in regulating branching morphogenesis or inducing cystic lung growth by inhibiting Wnt2/beta-catenin signaling. PMID:22261751
5. the role of KGF1 appeared to be exclusively concerned with increased proliferation and migration at the perforation site PMID:21136143
6. FGF10 regulates Meckel's cartilage formation during early mandibular morphogenesis by controlling the cell differentiation in the lateral area of the mandibular process in rats. PMID:21147086
7. data suggest that fibroblast growth factors FGF-7 and FGF-10 contribute to the regeneration and differentiation of acinar cells and angiogenesis in acute pancreatitis through the keratinocyte growth factor receptor PMID:12565793
8. Decreased gene expression of FGF-10 in the rat hypoplastic lung suggests that pulmonary hypoplasia in nitrofen-induced congenital diaphragmatic hernia rat may be caused by reduced synthesis of FGF-10 during lung morphogenesis. PMID:12861530
9. TGFbeta1 is regulator of Fgf10 expression in prostatic mesenchyme, and a proximal element within Fgf10 promoter plays an important role in its regulation and expression. PMID:14726452
10. Lateral prostate organ culture experiments demonstrate that growth and branching inhibition as well as Fgf10 suppression is mediated directly at the prostatic level. PMID:15680359
11. Role of Fgf10 in Androgen regulation of prostate morphoregultory gene expression. PMID:17218409
12. FGF10 positively regulates the beta-cell mass by increasing the proliferation of the early precursors and by extending the window of expression of an endocrine precursor. marker PMID:17923768
13. findings support a role for FGF10 in the induction of human congenital cystic adenomatoid malformation and provide further mechanistic insight into the role of FGF10 in normal and abnormal lung development PMID:18421016

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UNIGENE: Rn.44439

KEGG: rno:25443

STRING: 10116.ENSRNOP00000016485