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Recombinant Rat ETS-related transcription factor Elf-3 (Elf3)

Recombinant Rat ETS-related transcription factor Elf-3 (Elf3)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Elf3

Purity

>85% (SDS-PAGE)

Target Names

Elf3

Uniprot NO.

Q4V7E1

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-395

Target Protein Sequence

MAATCEISNV FSNYFNAMYS SEDPTLAPAP LTTFGTEDFV LTLNNQHMSP EGPVGCVGPQ TRSQRDRTEP PAVLHLAEKA SWTGERPQFW SKTQVLDWIS YQVEKNKYDA SSIDFSRCDM DGATLCNCAL EELRLVFGPL GDQLHAQLRD LTSSSSDELS WIIELLEKDG MTFQEGLGDS GPFDQGSPFA QELLDDGRQA SPYYGSSYGP GAPSPGSSDF STSGTDTPQS SHSSDSGGSD VDLDLTDSKV FPRDGFPDYK KGEPKHGKRK RGRPRKLSKE YWDCLEGKKS KHAPRGTHLW EFIRDILIHP ELNEGLMKWE NRHEGVFKFL RSEAVAQLWG QKKKNSNMTY EKLSRAMRYY YKREILERVD GRRLVYKFGK NSSGWKEEEV GESQN
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development.

Subcellular Location

Cytoplasm. Nucleus.

Protein Families

ETS family

Database Links

UNIGENE: Rn.3063

KEGG: rno:304815

STRING: 10116.ENSRNOP00000008753

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