Recombinant Rat Dystrophin (Dmd), partial

1. that decreased expression of dystrophin and increased expression of calpains are coincident and could work as possible therapeutic targets to prevent heart failure as a consequence of cardiac hypertrophy PMID:29267303
2. results show that dystrophin 71d, dystrophin 71f and dystrophin-associated protein integrate protein complexes, and both complexes were associated to nuclear speckles structures. PMID:26378780
3. Dp40 can interact with beta-dystroglycan as observed by co-localization assays and the co-localization was reduced with Dp40 mutants. PMID:26004254
4. Hypoxia-induced muscle damage is not accompanied by the loss of dystrophin and desmin. PMID:20717635
5. Dp71 is a component of the mitotic spindle and cytokinesis multi-protein apparatuses that might modulate the cell division cycle by affecting lamin B1 and beta-dystroglycan levels. PMID:21886794
6. This study found that cells stably expressing Dp71Delta(78-79) (PC12-C11) differentiate more efficiently than non-transfected cells. PMID:21668890
7. we established by immunoprecipitation assays that Dp71 and the dystrophin-associated proteins form a dystrophin-associated protein complex in the cell nucleus. PMID:19784870
8. dysfunction of dystrophin may result in endothelial and astroglial damage leading to vasogenic edema that is involved in pathogenesis of epileptogenesis PMID:21029730
9. SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes. PMID:21164104
10. results reveal a crucial role of MMP-mediated beta-DG cleavage in autoimmune neuritis, such as Guillain-Barre' syndrome, and bring insights into therapeutic strategies for autoimmune diseases. PMID:20097170
11. Components of dystrophin-dystroglycan complex were also distributed along the blood vessels of the pineal gland PMID:19924636
12. the distribution of dystrophin in series-fibred muscles suggests they are involved in transmission of tension from PMID:12037582
13. expression of dystrophin during skeletal muscle regeneration PMID:12086334
14. During a cycle of regeneration in tibialis anterior muscle following myonecrosis, dystrophin is found to be weakly labeled at the sarcolemma on day 5 and moderately stained on day 7. PMID:12416719
15. Loss of sarcolemmal dystrophin may be involved in the mechanism of contractile force-induced reperfusion injury. PMID:12890920
16. Results present immunocytochemical localization of beta-dystroglycan, the central member of the dystrophin glycoprotein complex, and show that beta-dystroglycan and utrophin are colocalized in clusters in all parts of Muller cells. PMID:14711029
17. Cardioprotection conferred by ischemic preconditioning may be enhanced by temporary blockade of contractile activity until restoration of membrane dystrophin during reperfusion. PMID:15001448
18. Dmd deficient PC12 cells generated by addition of antisense-Dp71 cells exhibited a marked suppression of neurite outgrowth. Early responses were normal, late responses were disturbed. PMID:15149856
19. Dp71 protein contributes to the proper functioning of the cerebrospinal fluid and blood-brain barriers PMID:15501597
20. These data support the notion of a physiological role of Dp71f distinct from other dystrophin isoforms present in the central nervous system. PMID:16841465
21. evaluation of the effect of repeated bouts of exercise on on skeletal muscle titin, desmin & dystrophin; desmin and dystrophin mRNA levels were increased after the first and fifth sessions PMID:17436058
22. Dp71f modulates GSK3-beta recruitment to the beta1-integrin adhesion complex. PMID:18677563
23. Dp71d is a dynamic component of nuclear matrix that might participate in the nuclear modeling occurring during neuronal differentiation. PMID:18687308
24. Findings demonstrate the interdependence between laminin binding to dystroglycan and GM1-containing lipid raft reorganization and provide novel insight into the dystrophin complex regulation of AQP4 polarization in astrocytes. PMID:19451651
25. dystrophin Dp71f is important for the function that the beta1-integrin complex has during neurite outgrowth PMID:19681445

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UNIGENE: Rn.10307

STRING: 10116.ENSRNOP00000029969