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Recombinant Rat Calcium-activated potassium channel subunit beta-2 (Kcnmb2), partial

Recombinant Rat Calcium-activated potassium channel subunit beta-2 (Kcnmb2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

Kcnmb2

Purity

>85% (SDS-PAGE)

Target Names

Kcnmb2

Uniprot NO.

Q811Q0

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex.

Gene References into Functions

Kcnmb2 is responsible for inactivating large-conductance calcium-dependent potassium currents in small sensory dorsal root ganglion neurons. PMID:17523149

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Subcellular Location

Membrane; Multi-pass membrane protein.

Protein Families

KCNMB (TC 8.A.14.1) family, KCNMB2 subfamily

Tissue Specificity

Highly expressed in brain and heart. Also expressed in lung.

Database Links

UNIGENE: Rn.220612

KEGG: rno:294961

STRING: 10116.ENSRNOP00000013410

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