Recombinant Rat Ataxin-1 (Atxn1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Atxn1

Purity

>85% (SDS-PAGE)

Target Names

Atxn1

Uniprot NO.

Q63540

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-789

Target Protein Sequence

MKSNQERSNE CLPPKKREIP ATSRPSEEKA TALPSDNHCV EGVAWLPSTP GSRGHGGGRH GPAGTSGEHG LQGMGLHKAL SAGLDYSPPS APRSVPTANT LPTVYPPPQS GTPVSPVQYA HLSHTFQFIG SSQYSGPYAG FIPSQLISPP GNPVTSAVAS AAGATTPSQR SQLEAYSTLL ANMGSLSQAP GHKVEPPPQQ HLGRAAGLVN PGSPPPTQQN QYIHISSSPQ SSGRATSPPI PVHLHPHQTM IPHTLTLGPS SQVVVQYSDA GGHFVPREST KKAESSRLQQ AMQAKEVLNG EMEKSRRYGA SSSVELSLGK TSSKSVPHPY ESRHVVVHPS PADYSSRDTS GVRGSVMVLP NSSTPSADLE TQQATHREAS PSTLNDKSGL HLGKPGHRSY ALSPHTVIQT THSASEPLPV GLPATAFYAG AQPPVIGYLS SQQQAITYAG GLPQHLVIPG TQPLLIPVGS PDMDTPGAAS AIVTSSPQFA AVPHTFVTTA LPKSENFNPE ALVTQAAYPA MVQAQIHLPV VQSVASPAAA SPTLPPYFMK GSIIQLANGE LKKVEDLKTE DFIQSAEISN DLKIDSSTVE RIEDSHSPGV AVIQFAVGEH RAQVSVEVLV EYPFFVFGQG WSSCCPERTS QLFDLPCSKL SVGDVCISLT LKNLKNGSVK KGQPVDPASA LLKHAKTDSL AGSRHRYAEQ ENGINQGSAQ VLSENGELKF PEKIGLPAAP FLTKIEPSKP TATRKRRWSA PETRKLEKSE DEPPLTLPKP SLIPQEVKIC IEGRSNVGK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved brain development.

Gene References into Functions

CD24 and Sca-1 in the mammary glands were expressed at lower level in 6-week-old female rats than in 9-week-old female rats. PMID:17545040
expression of SCA1 gene is prominent in LH-producing cells and is not under direct control of gonadal factor(s) in both genders PMID:15514462

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Subcellular Location

Cytoplasm. Nucleus.

Protein Families

ATXN1 family

Database Links

UNIGENE: Rn.88438

KEGG: rno:25049

STRING: 10116.ENSRNOP00000023140

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