Recombinant Rat Antizyme inhibitor 1 (Azin1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Azin1

Purity

>85% (SDS-PAGE)

Target Names

Azin1

Uniprot NO.

Q63764

Alternative Names

Azin1; Oazi; OazinAntizyme inhibitor 1; AZI; Ornithine decarboxylase antizyme inhibitor

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-448

Target Protein Sequence

MKGFIDDANY SVGLLDEGTN LGNVIDNYVY EHTLTGKNAF FVGDLGKIVK KHSQWQNVVA QIKPFYMVKC NSTPAVLEIL AALGTGFACS TKNEMALVQE LGVSPENIIY TSPCKQASQI KYAAKVGVNI MTCDNEVELK KIARNHPNAK VLLHIATEDN IGGEDGNMKF GTTLKNCRHL LECAKELDVQ IIGVKFHISS ACKEYQVYVH ALSDARCVFD MAGEFGFTMN MLDIGGGFTG TEIQLEEVNH VISPLLDIYF PEGSGIQIIS EPGSYYVSSA FTLAVNIIAK KVVENDKLSS GVEKNGSDEP AFVYYMNDGV YGSFASKLSE DLNTVPEVHK KYKEDEPLFT SSLWGPSCDE LDQIVESCLL PELSVGDWLI FDNMGADSLH GPSAFSDTQR PAIYFMMSLS DWYEMQDAGI TSDAMMKNFF FAPSCIQLSQ EDNFSTEA
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

Subcellular Location

Nucleus.

Protein Families

Orn/Lys/Arg decarboxylase class-II family, ODC antizyme inhibitor subfamily

Tissue Specificity

Expressed in various tissues including liver, heart and kidney.

Database Links

UNIGENE: Rn.6290

STRING: 10116.ENSRNOP00000007999

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