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Recombinant Rat Adrenocortical dysplasia protein homolog (Acd)

Recombinant Rat Adrenocortical dysplasia protein homolog (Acd)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

Acd

Purity

>85% (SDS-PAGE)

Target Names

Acd

Uniprot NO.

Q4FZR5

Alternative Names

AcdAdrenocortical dysplasia protein homolog

Species

Rattus norvegicus (Rat)

Source

Yeast

Expression Region

1-417

Target Protein Sequence

MSNSGRLVLR PWIRELILGS ETLSSPQAGH LLKVLQDSET PGPSSAPDTP DTGAVLLVSD GTHSVRCVVT RNAIDTSDWE EKEFGFRGTE GRLLLLQACG LRIQVAQDYA PAEFYLQVDR FNLLPTEQPR VQVTGCNQDS DVQKKLNKCL EDHLSESASS SAGLTLSQLL DEVKEDGDHR GALVRLAESC LVLQGPFTAR PLTHWATSCS QATEEAVFTV PSFLLHISEN EEQILSSIDS SQKAQENPAS PSLMPQEESG ASVSLLSALP TSDPGQKDNS QPPPTVCSTS PRAQAPSSTP CSSTPSSPLL TCSPSLSPLR HAPTSYQACE TRTQFHKLEF RELQWPIKRR QLLPRTGAQE PHSVWEPPER HRDTSAFQYK YGTPSASLHT QVQTARLSPQ LVAWALNIVM ESELPQV
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

Subcellular Location

Nucleus. Chromosome, telomere.

Database Links

UNIGENE: Rn.8611

KEGG: rno:307798

STRING: 10116.ENSRNOP00000056334

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