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Recombinant Rat Adenylate cyclase type 3 (Adcy3), partial

Recombinant Rat Adenylate cyclase type 3 (Adcy3), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

Adcy3

Uniprot NO.

P21932

Alternative Names

Adcy3Adenylate cyclase type 3; EC 4.6.1.1; ATP pyrophosphate-lyase 3; Adenylate cyclase type III; AC-III; Adenylate cyclase; olfactive type; Adenylyl cyclase 3; AC3

Species

Rattus norvegicus (Rat)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.

Gene References into Functions

Here is formulated an active site model for the mammalian adenylyl cyclase class III, which is used to describe the potential surface along the reaction trajectory for enzyme-catalyzed conversion of ATP to cAMP. PMID:26393535
AC3 plays a role in regulation of glucose homeostasis via CNS and insulin secretion. PMID:23018249
adenylyl cyclase 3 is functional in rodent oocytes and its activity is involved in the control of oocyte meiotic arrest PMID:12798295
Data show that adenylate cyclase 3 type III is enriched in the ciliary membrane fraction. PMID:18596612