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Recombinant Rabbit Non-selective voltage-gated ion channel VDAC2 (VDAC2), partial

Recombinant Rabbit Non-selective voltage-gated ion channel VDAC2 (VDAC2), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

VDAC2

Uniprot NO.

P68003

Alternative Names

VDAC2; Voltage-dependent anion-selective channel protein 2; VDAC-2; Outer mitochondrial membrane protein porin 2

Species

Oryctolagus cuniculus (Rabbit)

Source

Yeast

Expression Region

1-36aa

Target Protein Sequence

MATYGQPCARPMCIPPSYADLGKAARDIFNKGFGFG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Buffer

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol. Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway.

Subcellular Location

Mitochondrion outer membrane. Membrane.

Protein Families

Eukaryotic mitochondrial porin family

Database Links

UNIGENE: Ocu.599

KEGG: ocu:100009473

STRING: 9986.ENSOCUP00000007848

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