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Recombinant Rabbit Parathyroid hormone-related protein (PTHLH)

Recombinant Rabbit Parathyroid hormone-related protein (PTHLH)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

PTHLH

Purity

>85% (SDS-PAGE)

Target Names

PTHLH

Uniprot NO.

Q9GLC7

Species

Oryctolagus cuniculus (Rabbit)

Source

Yeast

Expression Region

37-177

Target Protein Sequence

AVSE HQLLHDKGKS IQDLRRRFFL HHLIAEIHTA EIRATSEVSP NSKPAANTKN HAVRFGSDDE GRYLTQETNK VEPYKEQPLK TPGKKKKGKP GKRKEQEKKK RRTRSAWPLS AGAGSGLAGD HLSDISEPEP ELDSRRH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.; Osteostatin is a potent inhibitor of osteoclastic bone resorption.

Subcellular Location

Cytoplasm. Nucleus. Secreted.

Protein Families

Parathyroid hormone family

Database Links

UNIGENE: Ocu.2489

KEGG: ocu:100009357

STRING: 9986.ENSOCUP00000011922

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