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Recombinant Rabbit Insulin (INS), partial

Code
MSDS
MSDS Datasheet
Size Pls inquire
Source
Conjugate
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
INS
Uniprot NO.
Alternative Names
INS; Insulin [Cleaved into: Insulin B chain; Insulin A chain]
Species
Oryctolagus cuniculus (Rabbit)
Source
Yeast
Expression Region
25-54
Target Protein Sequence
FVNQHL CGSHLVEALY LVCGERGFFY TPKS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
Gene References into Functions
  1. insulin supports early initiation of the mesodermal factor Brachyury and the signalling molecules Wnt3a and Wnt4 as well as the progression of mesoderm formation PMID:21827825
  2. Data show that type 1 diabetic blastocyst did not express insulin mRNA. PMID:20631000

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Subcellular Location
Secreted.
Protein Families
Insulin family
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Related pathways
HIF-1 signaling pathwayMAPK signaling pathwaymTOR signaling pathwayPI3K-Akt signaling pathwayRegulation of actin cytoskeletonAutophagyRas signaling pathwayAMPK signalingcGMP-PKG signaling pathwayFoxO signaling pathwayInsulin signaling pathwayPhospholipase D signaling pathwayRap1 signaling pathway
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