Recombinant Rabbit Coagulation factor VII(F7), partial

Code
MSDS
Size Pls inquire
Source
Conjugate
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
F7
Uniprot NO.
Alternative Names
F7Coagulation factor VII; EC 3.4.21.21; Serum prothrombin conversion accelerator) [Cleaved into: Factor VII light chain; Factor VII heavy chain]
Species
Oryctolagus cuniculus (Rabbit)
Source
Yeast
Expression Region
40-191
Target Protein Sequence
A NSFLEELRPG SLERECKEEL CSFEEAREVF QSTERTKQFW ITYNDGDQCA SNPCQNGGSC EDQIQSYICF CLADFEGRNC EKNKNDQLIC MYENGGCEQY CSDHVGSQRS CRCHEGYTLL PNGVSCTPTV DYPCGKVPAL EKRGASNPQG R
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Buffer
Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Gene References into Functions
  1. Results suggest that inhibition of FVIIa with small-molecule active-site inhibitors represents a promising antithrombotic approach. PMID:20589312

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Subcellular Location
Secreted.
Protein Families
Peptidase S1 family
Tissue Specificity
Plasma.
Database Links
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