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Recombinant Rabbit Aryl hydrocarbon receptor nuclear translocator (ARNT), partial

Recombinant Rabbit Aryl hydrocarbon receptor nuclear translocator (ARNT), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

ARNT

Uniprot NO.

O02748

Species

Oryctolagus cuniculus (Rabbit)

Source

Yeast

Expression Region

2-790

Target Protein Sequence

AATTANPEM TSDVPSLGPN ITSGNPGPAI QGGGTIVQRA VKRRPGLDFD DDGEGNSKFL RCDEDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDIVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ SSMRMCMGSR RSFICRMRCG NSSVDPVSMN RLSFVRNRCR NGLGSVKDGE PHFVVVHCTG YIKAWPPAGV SLPDDDPEAG QGSKFCLVAI GRLQVTSSPN CTDMSNVCQP TEFISRHNIE GIFTFVDHRC VATVGYQPQE LLGKNIVEFC HPEDQQLLRD SFQQVVKLKG QVLSVMFRFR SKNREWLWTR TSSFTFQNPY SDEIEYIICT NTNVKNSSQE PRPTLSNPIQ RPQLGPTANL PLEVGSGQLA PRQQQQQTEL DMVPGRDGLT NYNHSQISVQ PVATTGPEHG KPLEKSDSLF AQDRDPRFSE MYSNINADQS KGISSSTVPA TQQLFSQGNT FPPNPRPAEN FRNSGLAPPV TIVQASASAG EMLAQISRHS NPTQGTAPTW TPSTRPGFSA QQVASQATTK SRSSQFGVGN FQSPSSFSSM SLSSTSTASS GAAAYPSLTS RGSNFAPETG QTAGQFQTRT AEGVGVWPQW QGQQPHHRST SSEQHVQQPS TQQPNQPEVF QEMLSMLGDQ SSSYNNEEFP DLTMFPSFSE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters and functions as a transcriptional regulator of the adaptive response to hypoxia. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription.

Subcellular Location

Nucleus.

Tissue Specificity

Was expressed at almost the same level in all tissues except for the heart, liver, and small intestine.

Database Links

UNIGENE: Ocu.2135

KEGG: ocu:100008996

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