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Recombinant Rabbit ADP-ribosyl cyclase 1 (CD38), partial

Recombinant Rabbit ADP-ribosyl cyclase 1 (CD38), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details

Abbreviation

CD38

Purity

>85% (SDS-PAGE)

Target Names

CD38

Uniprot NO.

Q9MZ03

Species

Oryctolagus cuniculus (Rabbit)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity.

Gene References into Functions

Data, including data from studies on cells from knockout mice, suggest that intracellular CD38 contributes to NAADP production and cADPR production in cardiomyocytes; membrane fractions from wildtype but not CD38-/- mouse hearts support NAADP and cADPR synthesis; CD38 may be associated with sarcoplasmic reticulum of cardiomyocytes. (NAADP = nicotinate adenine dinucleotide phosphate; cADPR = cyclic ADP-ribose) PMID:28539361

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Subcellular Location

Cell membrane; Single-pass type II membrane protein. Microsome membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Protein Families

ADP-ribosyl cyclase family

Tissue Specificity

Osteoclasts.

Database Links

UNIGENE: Ocu.1561

KEGG: ocu:100009409

STRING: 9986.ENSOCUP00000015283

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