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Recombinant Pyrococcus kodakaraensis DNA double-strand break repair Rad50 ATPase (rad50), partial

Recombinant Pyrococcus kodakaraensis DNA double-strand break repair Rad50 ATPase (rad50), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

rad50

Purity

>85% (SDS-PAGE)

Target Names

rad50

Uniprot NO.

Q5JHN1

Alternative Names

rad50; TK2211; DNA double-strand break repair Rad50 ATPase

Species

Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))

Source

Yeast

Expression Region

1-883

Target Protein Sequence

MKIEKLIIKD FRSHALTKVN FSSGINLIIG QNGSGKSSIL DALLVGLYWP SKPKDLKKDD FERINGSGTE ITVFFEKGNV KYQIHRNIGR GLAFVKYHDG SSWKTLETGQ KPVRDWMEKL VPYDVFLNAI YIRQGEIDAI LESDESREKV VRQVLGLDRY ENSYKNLLDV RKEIDARIKA IEDYLKSTEN IDELIGNLEK ELTSVLREIN EISPKLPELR GELGGLEKEL KELEKTAEEL AKARVELKSE EGNLRELEAK KSGIQSMIRE TEKRVEELKE KVKELESLEE KAKEYERLSR FYRNFTEGIN RIEKLLATYS QQAENLRERI DELSKKEARV KELLKEKEGL QKELGALEED LKAYQRAKEL MANLERLKKR LTLSEEEIEK LEAEIQKARE RKEEIMKELE EIGSRRGELK SIAGERNKAL MELKKAKGRC PVCGRELTEE HRKELLEKYT AELKEISAEM KELEKREKKL RAELVEVEKT LKKERELFAL KEVLEQIRET EEKLKEYDLE KLEEANEKAE ELKKKLAGLE GEIKSLEDEI KKGELLKKKL ALVEKKLREL EEERASLLGE LKKLGFGDVK ELEERLKELE PAYKRYIELR PARDELKREE DLLKSLKLDL TAILKEIEKT SKRVEELRKR VEELEKSYDK DRHEELKGKT RELSNELAGL EARLKSLEER RDEVKASLEK LREEKETRKE KAKELEKLKK ARERVQRLRE KVKAYKNLLK EGALAKVGEM ASEIFEELTE EKYSGVTVKA EENKVRLGVV YNGKEYGLGF LSGGERIALG LAFRLALSLY LAGEISLLIL DEPTPYLDEE RRRRLVDIMQ RYLRKIPQVI VVSHDEELKD AADRVIRVSL ENGVSVVREA EVG
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.

Protein Families

SMC family, RAD50 subfamily

Database Links

KEGG: tko:TK2211

STRING: 69014.TK2211

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