Recombinant Pongo pygmaeus Complement decay-accelerating factor (CD55)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
CD55
Uniprot NO.
Alternative Names
CD55; DAFComplement decay-accelerating factor; CD antigen CD55; Fragment
Species
Pongo pygmaeus (Bornean orangutan)
Source
Yeast
Expression Region
1-312
Target Protein Sequence
VPNAQPALEG RTSFPEDTVV TYKCEESFMK IPGKKDSVIC LKGSQWSDIE EFCNRSCEVP TRLNFASLKQ PYITQNYFPV GTTVEYVCRP GYRRELSLST KLTCLQNLTW STAVEFCKKK SCPNPGEIRN GQIDVSNGIL FGATISFSCN TGYKLFGPTS SLCLISGSSV QWSDPLPECR EIYCPAPPQI DNGIIQGKRD HYGYRQSITY ACNKGYTMIG EHSIYCTVND DEGEWSGPPP ECRGKSLTSK VPPTVQKPTT VNVPTTEVSP TSQKTTTKTT TPNAQATRST PVSRTTKHFH ETTPNKGSGT TS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage.
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Receptors of complement activation (RCA) family
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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