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Recombinant Pongo abelii Autophagy-related protein 16-1 (ATG16L1), partial

Recombinant Pongo abelii Autophagy-related protein 16-1 (ATG16L1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

ATG16L1

Purity

>85% (SDS-PAGE)

Target Names

ATG16L1

Uniprot NO.

Q5RAC9

Alternative Names

ATG16L1; APG16LAutophagy-related protein 16-1; APG16-like 1

Species

Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Source

Yeast

Expression Region

1-607

Target Protein Sequence

MSSGLRAADF PRWKRHISEQ LRRRDRLQRQ AFEEIILQYN KLLEKSDLHS VLAQKLQAEK HDVPNRHEIS PGHDGTWNDS QLQEMAQLRI KHQEELTELH KKRGELAQLV IDLNNQMQRK DREMQMNEAK IAECLQTISD LETECLDLRT KLCDLERANQ TLKDEYDALQ ITFTALEGKL RKTTEENQEL VTRWMAEKAQ EANRLNAENE KDSRRRQARL QKELAEAAKE PLPVEQDDDI EVIVDETSDH TEETSPVRAI SRAATKRLSQ PAGGLLDSIT NIFGRRSVSS FPVPQDNVDT HPGSGKEVRV PTTALCVFDA HDGEVNAVQF SPGSRLLATG GMDRRVKLWE VFGEKCEFKG SLSGSNAGIT SIEFDSAGSY LLAASNDFAS RIWTVDDSRL RHTLTGHSGK VLSAKFLLDN ARIVSGSHDR TLKHWDLRSK VCIKTVFAGS SCNDIVCTEQ CVMSGHFDKK IRFWDIRSES IVREMELLGK ITALDLNPER TELLSCSRDD LLKVIDLRTN AIKQTFSAPG FKCGSDWTRV VFSPDGSYVA AGSAEGSLYT WSVLTGKVEK VLSKQHSSSI NAVAWSPSGL HVVSVDKGCK AVLWAQY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway. Plays a role in regulating morphology and function of Paneth cell.

Subcellular Location

Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.

Protein Families

WD repeat ATG16 family

Database Links

UNIGENE: Pab.555

KEGG: pon:100172682

STRING: 9601.ENSPPYP00000014856

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