Recombinant Pig Transthyretin (TTR)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

TTR

Uniprot NO.

P50390

Species

Sus scrofa (Pig)

Source

Yeast

Expression Region

21-150

Target Protein Sequence

GPAGAGESKC PLMVKVLDAV RGSPAVNVGV KVFKKAADGT WEPFALGKTS EFGELHGLTT DEKFVEGIYK VELDTKSYWK ALGISPFHEY AEVVFTANDS GRRHYTIAAL LSPYSYSTTA LVSSPKEGAL
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Gene References into Functions

The rank order potency of the chemicals tested for the displacement of [125I]TIP from TTR was TIP > ioxynil > pentachlorophenol, T4, and retinoic acid > tetrabromobisphenol A, diethylstilbestrol, and T3. PMID:21147258
This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, SAA and transthyretin. PMID:17629575

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Subcellular Location

Secreted.

Protein Families

Transthyretin family

Tissue Specificity

Detected in plasma and cerebrospinal fluid (at protein level). Highly expressed in the choroid plexus. Detected in liver.

Database Links

UNIGENE: Ssc.52340

KEGG: ssc:397419

STRING: 9823.ENSSSCP00000022931

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