Recombinant Pig Sodium/hydrogen exchanger 1 (SLC9A1)

Product Details

Purity
>85% (SDS-PAGE)
Target Names
SLC9A1
Uniprot NO.
Alternative Names
SLC9A1; NHE1; Sodium/hydrogen exchanger 1; Na(+)/H(+) exchanger 1; NHE-1; Solute carrier family 9 member 1
Species
Sus scrofa (Pig)
Source
Yeast
Expression Region
1-818
Target Protein Sequence
MLLWSGICGLSPPRIFPSLLVVVALVGLLPVLRSHGLQPSPTASTIRGSEPPRERSIGDV TTAPPELAPESRPVNHSVTEHGMKARKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFH VIPTISSIVPESCLLIVVGLLVGGLIKAVGETPPFLQSEVFFLFLLPPIILDAGYFLPLR QFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPV AVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYDRVGIVDIVLGFLSFFV VSLGGVFVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASG VVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLF CLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGHLLDKNHFPMCDLF LTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGH YGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSA VSTVSMQNIHPKTLPTERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYE EAWNQMLLRRQKARQLEQKINNHLTVPAHKLDSPTMSRARIGSDPLAYEPKADLPVITID PASPQSPESVDLVNEELKGKVLGLSREPGRATEEEDDDEDHDGGLVMRTKEPSSPGTDDV FTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFIPKGQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
Protein Length
Full length protein
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage Condition
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

 Customer Reviews

Target Background

Function(From Uniprot)
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
Gene References into Functions
  1. NHE isoform switching and KChIP2 upregulation takes place in aging porcine atria. PMID:24376615
  2. NHE-1 inhibitor cariporide attenuates skeletal muscle infarction when administered before ischemia or reperfusion. PMID:19023020

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Subcellular Location
Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein Families
Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family
Database Links
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