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Recombinant Pig Plasminogen activator inhibitor 1 (SERPINE1)

Recombinant Pig Plasminogen activator inhibitor 1 (SERPINE1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

SERPINE1

Uniprot NO.

P79335

Species

Sus scrofa (Pig)

Source

Yeast

Expression Region

24-402

Target Protein Sequence

SSHHQSL AARLATDFGV KVFRQVVQAS KDRNVVFSPY GVASVLAMLQ LTTAGDTQQQ IQEAMQFKIE EKGMAPALRQ LYKELMGPWN KDEISTADAI FVQRDLKLVQ GFMPYFFRLF RTTVKQVDFS EMDRARFIIN DWVKRHTKGM INDLLGQGAV DQLTRLVLVN ALYFNGQWKT PFPEKSTHHR LFHKSDGSTV SVPMMAQTNK FNYTEFSTPD GHYYDILELP YHGNTLSMFI AAPYEKEVPL SALTSILDAQ LISQWKGNMT RLTRLLVLPK FSLESEVDLR RPLENLGMTD MFRPNQADFS SLSDQELLYM SQALQKVKIE VNESGTVASS STAIIVSARM APEEIIMDRP FLFVVRHNPT GTVLFMGQVM EP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function(From Uniprot)

Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.

Gene References into Functions

In one pig population and in female pigs, SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1) was significantly associated with muscling, growth and fat accretion and in male animals with meat quality. PMID:22497544

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Subcellular Location

Secreted.

Protein Families

Serpin family

Database Links

UNIGENE: Ssc.9781

KEGG: ssc:396945

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