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Recombinant Pig Nuclear receptor subfamily 6 group A member 1 (NR6A1)

Recombinant Pig Nuclear receptor subfamily 6 group A member 1 (NR6A1)

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

NR6A1

Uniprot NO.

A0P8Z4

Species

Sus scrofa (Pig)

Source

Yeast

Expression Region

1-479

Target Protein Sequence

MERDERPPSG GGGGGGSAGF LEPPAALPPP PRNGFCQDEL AELDPSTISV PDDRAEQRTC LICGDRATGL HYGIISCEGC KGFFKRSICN KRVYRCSRDK NCVMSRKQRN RCQYCRLLKC LQMGMNRKAI REDGMPGGRN KSIGPVQISE EEIERIMSGQ EFEEEANHWS NHGDSDHSSP GNRASESNQP SPGSTLSSRS VELNGFMAFR DQYMGMSVPP HYQYIPHLFS YSAHSPLLPP QARSLDPQSY SLIHQLVSAE DLEPLGTPML IEDGYAVTQA ELFALLCRLA DELLFRQIAW IKKLPFFCEL SIKDYTCLLS STWQELILLS SLTVYSKQIF GELADVTAKY SPSDEELHRF SDEGMEVIER LIYLYHKFHQ LKVSNEEYAC MKAINFLNQD IRGLTSASQL EQLNKRYWYI CQDFTEYKYT HQPNRFPDLM MCLPEIRYIA GKMVNVPLEQ LPLLFKVVLH SCKTSVGKE
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.

Gene References into Functions

NR6A1, PLAG1 and VRTN are significantly associated with the number of vertebrae in Chinese Tongcheng x Large White crossbred pigs PMID:29774581
Recent studies suggest that a missense substitution (p.Pro192Leu) in the nuclear receptor subfamily 6, group A, member 1 (NR6A1) gene, mapped on porcine chromosome 1, is the causative mutation of a QTL affecting the number of vertebrae in pigs. PMID:25134014
this study supports the assumption that the Western NR6A1 haplotypes were introduced into Licha Black and possibly Laiwu and are associated with increased vertebral number PMID:19220230

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Subcellular Location

Nucleus.

Protein Families

Nuclear hormone receptor family, NR6 subfamily

Database Links

UNIGENE: Ssc.51714

KEGG: ssc:100038028

STRING: 9823.ENSSSCP00000005986

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