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Recombinant Pig Interleukin-23 subunit alpha (IL23A)

Recombinant Pig Interleukin-23 subunit alpha (IL23A)

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

IL23A

Purity

>85% (SDS-PAGE)

Target Names

IL23A

Uniprot NO.

Q9N2H9

Alternative Names

IL23A; SGRF; Interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; Interleukin-23 subunit p19; IL-23p19

Species

Sus scrofa (Pig)

Source

Yeast

Expression Region

23-193

Target Protein Sequence

RAVPEGSS PAWAQGQQLS QQLCTLAWTA HLPMGHVDLP REEGDDETTS EVPHIQCGDG CDPQGLRDNS QSCLQRIHQG LVFYEKLLGS DIFTGEPSLH PDGSVGQLHA SLLGLRQLLQ PEGHHWETEQ TPSPSPSQPW QRLLLRLKIL RSLQAFVAVA ARVFAHGAAT LSQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Gene References into Functions

These results provide genetic information about both swine IL-23 the IL-23 receptor alpha (IL-23Ralpha) and IL-12 receptor beta1 (IL-12Rbeta1), which allows for better understanding of interleukin systems involved in pig immunity. PMID:22032895

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Subcellular Location

Secreted.

Protein Families

IL-6 superfamily

Database Links

UNIGENE: Ssc.56047

KEGG: ssc:100155546

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