Recombinant Pig Interferon alpha/beta receptor 1 (IFNAR1), partial

Product Details

Abbreviation
IFNAR1
Purity
>85% (SDS-PAGE)
Target Names
IFNAR1
Uniprot NO.
Species
Sus scrofa (Pig)
Source
Yeast
Protein Length
Partial
Tag Info
N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)
Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.
Gene References into Functions
  1. The complete 168,835 bp insert sequence of a porcine BAC clone harboring the IFNAR1 gene was determined. PMID:17065794

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Subcellular Location
Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome.
Protein Families
Type II cytokine receptor family
Database Links

UNIGENE: Ssc.11381

KEGG: ssc:396658

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