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Recombinant Pig Estrogen receptor beta (ESR2), partial

Recombinant Pig Estrogen receptor beta (ESR2), partial

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Target Background

Product Details

Abbreviation

ESR2

Purity

>85% (SDS-PAGE)

Target Names

ESR2

Uniprot NO.

Q9XSW2

Alternative Names

ESR2; NR3A2Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2

Species

Sus scrofa (Pig)

Source

Yeast

Expression Region

1-526

Target Protein Sequence

MDIKNSPSNL NSPVSYNCSQ SVLPLEPGPI YIPSSYVESC HEYSAMTFYS PAVVNYSISS NSEVGPGRQA TSPNVLWPTP GHLSPLAIHC QPSLLYAEPQ KSPWCDTRSL EHTLPVNRET LKRKASGSSC ASPVTSPSSK RDAHFCAVCS DYASGYHYGV WSCEGCKAFF KRSIQGHNDY ICPATNQCTI DKNRRKSCQA CRLRKCYEVG MVKCGSRRER CGYRIVRKQR NSEGHLHCLS RAKKNGDHTT RVKELLLSTL SPEQLVLTLL EAEPPHVLVS RPSTPFTEAS MMMSLTKLAD KELVHMISWA KKIPGFMELS LYDQVRLLES CWLEVLMVGL MWRSIDHPGK LIFAPDLVLD RDEGKCVEGI LEIFDMLLAT TSRFRELKLQ HKEYLCVKAM ILLNSSMYPS AAAQEAESSR KLTHLLNAVT DALVWVIARS GISSQQQSVR LANLLMLLSH VRHASNKGTE HLLNMKCKNV VPVYDLLLEM LNAHTLRGNK SLVTGSERSR MEESESKEGS QKPQAQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.

Gene References into Functions

There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found. PMID:27824510
steroid hormones, AhR and estrogen receptor beta are affected by TCDD and genistein in granulosa cells of medium porcine follicles PMID:26568065
Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 and PAR-2) associate with breast cancer outcome in an estrogen receptor (ER)-dependent manner. PMID:26244666
results might shed new light on the roles of estrogen receptor 2(ESR2) in spermatogenesis as candidate for boar fertility PMID:22212297
study is the first one to demonstrate the presence of estrogen receptors alpha and beta in the porcine uterus not only at the beginning but also at mid- and late pregnancy PMID:19645857
Downregulation of the ERs, particularly ERalpha in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus. PMID:14522825
the results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function PMID:15046395
findings suggest that testicular oestrogen receptors alpha and beta may be important factors contributing to onset and maintenance of spermatogenesis in the boar PMID:15943697
ERbeta mRNA was found only in Sertoli cells in the testis. PMID:16249893
positive staining for ERalpha in the nuclei of skeletal muscle cells, while the ERbeta stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells PMID:16897031
ESR2 gene polymorphisms are associated with litter size. PMID:16965408
The objective of this study was to search for polymorphisms in the coding region of the estrogen receptors 1 and 2 (ESR1 and ESR2) and to analyze the effects of these variants and the well known intronic ESR1 PvuII polymorphism on litter size. PMID:17306201
These data demonstrate novel and differential mechanisms by which ERalpha and ERbeta activation control coronary artery vasoreactivity in males and females and regulate vascular NO and O(2)(-) formation. PMID:17470727
Pig ejaculated spermatozoa express estrogen receptor. PMID:17553131
The expression of mRNAs for ERalpha, ERbeta and PR in the sow uterus differed between endometrium and myometrium as well as with stages of the estrous cycle and early pregnancy. PMID:18547755