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Recombinant Pig Coagulation factor XII (F12), partial

Recombinant Pig Coagulation factor XII (F12), partial

Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

F12

Uniprot NO.

O97507

Alternative Names

F12Coagulation factor XII; EC 3.4.21.38; Hageman factor; HAF) [Cleaved into: Coagulation factor XIIa heavy chain; Coagulation factor XIIa light chain]

Species

Sus scrofa (Pig)

Source

Baculovirus

Expression Region

20-371

Target Protein Sequence

I PPWKDPRKHK VMASEHTVVL TVTGEPCHFP FQYYRQLYYK CIQRGQRGPR PWCATTPNFE KDQRWAYCLE PMKVKDHCNK GNPCQKGGTC VNMPNGPHCI CPDHFTGKHC QKEKCFEPQF LQFFQENEIW HRFEPAGVSK CQCKGPKAQC KPVASQVCST NPCLNGGSCL QTEGHRLCRC PTGYAGRLCD VDLKERCYSD RGLSYRGMAQ TTLSGAPCQP WASEATYWNM TAEQALNWGL GDHAFCRNPD NDTRPWCFVW RGDQLSWQYC RLARCQAPIG EAPPILTPTQ SPSEHQDSPL LSREPQPTTQ TPSQNLTSAW CAPPEQRGPL PSAGLVGCGQ RLRKRLSSLN R
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

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Target Background

Function(From Uniprot)

Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

Subcellular Location

Secreted.

Protein Families

Peptidase S1 family

Database Links

UNIGENE: Ssc.749

KEGG: ssc:397474

STRING: 9823.ENSSSCP00000024170

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