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Recombinant Pan troglodytes Mediator of RNA polymerase II transcription subunit 12 (MED12), partial

Recombinant Pan troglodytes Mediator of RNA polymerase II transcription subunit 12 (MED12), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

MED12

Purity

>85% (SDS-PAGE)

Target Names

MED12

Uniprot NO.

Q7YQK8

Species

Pan troglodytes (Chimpanzee)

Source

Yeast

Expression Region

1-2027

Target Protein Sequence

MRAAWLIKMT CAYYAAISET KVKKRHVDPF MEWTQIITKY LWEQLQKMAE YYRPGPAGSG GCGSTIGPLP HDVEVAIRQW DYTEKLAMFM FQDGMLDRHE FLTWVLECFE KIRPGEDELL KLLLPLLLRY SGEFVQSAYL SRRLAYFCTR RLALQLDGVS SHSSHVISAQ STSTLPTTPA PQPPTSSTPS TPFSDLLMCP QHRPLVFGLS CILQTILLCC PSALVWHYSL TDSRIKTGSP LDHLPIAPSN LPMPEGNSAF TQQVRAKLRE IEQQIKERGQ AVEVRWSFDK CQEATAGFTI GRVLHTLEVL DSHSFERSDF SNSLDSLCNR IFGLGPSKDG HEISSDDDAV VSLLCEWAVS CKRSGRHRAM VVAKLLEKRQ AEIEAERCGE SEAADEKGSI ASGSLSAPSA PIFQDVLLQF LDTQAPMLTD PRSENERVEF FNLVLLFCEL IRHDVFSHNM YTCTLISRGD LAFGAPGPRP PSPFDDPADD AEHKEAEGSS SSKLEDPGLS ESMDIDPSSS VLFEDMEKPD FSLFSPTMPC EGKGSPSPEK PDVEKEVKPP PKEKIEGTLG ILYDQPRHVQ YATHFPIPQE ESCSHECNQR LVVLFGVGKQ RDDARHAIKK ITKDILKVLN RKGTAETDQL APIVPLNPGD LTFLGGEDGQ KRRRNRPEAF PTAEDIFAKF QHLSHYDQHQ VTAQVSRNVL EQITSFALGM SYHLPLVQHV QFIFDLMEYS LSISGLIDFA IQLLNELSVV EAELLLKSSD LVGSYTTSLC LCIVAVLRHY HACLILNQDQ MAQVFEGLCG VVKHGMNRSD GSSAERCILA YLYDLYTSCS HLKNKFGELF SDFCSKVKNT IYCNVEPSES NMRWAPEFMI DTLENPAAHT FTYTGLGKSL SENPANRYSF VCNALMHVCV GHHDPDRVND IAILCAELTG YCKSLSAEWL GVLKALCCSS NNGTCGFNDL LCNVDVSDLS FHDSLATFVA ILIARQCLLL EDLIRCAAIP SLLNAACSEQ DSEPGARLTC RILLHLFKTP QLNPCQSDGN KPTVGIRSSC DRHLLAASQN RIVDGAVFAV LKAVFVLGDA ELKGSGFTVT GGTEELPEEE GGGGSGGRRQ GGRNISVETA SLDVYAKYVL RSICQQEWVG ERCLKSLCED SNDLQDPVLS SAQAQRLMQL ICYPHRLLDN EDGENPQRQR IKRILQNLDQ WTMRQSSLEL QLMIKQTPNN EMNSLLENIA KATIEVFQQS AETGSSSGST ASNMPSSSKT KPVLSSLERS GVWLVAPLIA KLPTSVQGHV LKAAGEELEK GQHLGSSSRK ERDRQKQKSM SLLSQQPFLS LVLTCLKGQD EQREGLLTSL YSQVHQIVNN WRDDQYLDDC KPKQLMHEAL KLRLNLVGGM FDTVQRSTQQ TTEWAMLLLE IIISGTVDMQ SNNELFTTVL DMLSVLINGT LAADMSSISQ GSMEENKRAY MNLAKKLQKE LGERQSDSLE KVRQLLPLPK QTRDVITCEP QGSLIDTKGN KIAGFDSIFK KEGLQVSTKQ KISPWDLFEG LKPSAPLSWG WFGTVRVDRR VARGEEQQRL LLYHTHLRPR PRAYYLEPLP LPPEDEEPPA PTLLEPEKKA PEPPKTDKPG AAPPSTEERK KKSTKGKKRS QPATKTEDYG MGPGRSGPYG VTVPPDLLHH PNPGSITHLN YRQGSIGLYT QNQPLPAGGP RVDPYRPVRL PMQKLPTRPT YPGVLPTTMT GVMGLEPSSY KTSVYRQQQP AVPQGQRLRQ QLQAKIQSQG MLGQSSVHQM TPSSSYGLQT SQGYTPYVSH VGLQQHTGPA GTMVPPSYSS QPYQSTHPST NPTLVDPTRH LQQRPSGYVH QQAPTYGHGL TSTQRFSHQT LQQTPMISTM TPMSAQGVQA GVRSTAILPE QQQQQQQQQQ QQQQQQQQQQ QQQQQQYHIR QQQQQQILRQ QQQQQQQQQQ QQQQQQQQQQ QQQQQHQQQQ QQQAAPPQPQ PQSQPQFQRQ GLQQTQQQQQ TAALVRQLQQ QLSNTQPQPS TNIFGRY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Subcellular Location

Nucleus.

Protein Families

Mediator complex subunit 12 family

Database Links

UNIGENE: Ptr.6417

KEGG: ptr:449626

STRING: 9598.ENSPTRP00000047374

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