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Recombinant Pan troglodytes Hemoglobin subunit beta (HBB)

Recombinant Pan troglodytes Hemoglobin subunit beta (HBB)

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MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

HBB

Uniprot NO.

P68873

Alternative Names

HBB; Hemoglobin subunit beta; Beta-globin; Hemoglobin beta chain

Species

Pan troglodytes (Chimpanzee)

Source

Yeast

Expression Region

2-147

Target Protein Sequence

VHLTPEEKS AVTALWGKVN VDEVGGEALG RLLVVYPWTQ RFFESFGDLS TPDAVMGNPK VKAHGKKVLG AFSDGLAHLD NLKGTFATLS ELHCDKLHVD PENFRLLGNV LVCVLAHHFG KEFTPPVQAA YQKVVAGVAN ALAHKYH
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Full Length of Mature Protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

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■ Q&A

Do you have them: HBB?
I am looking for the control protein for HbH (β4) and Barts (γ4) · I am studying the haemoglobin variants and I couldn't able to find these two controls for my study. The closest protein I found is HBG1.HBG2 for barts and HBB for HbH. However, I am not sure whether this is the right protein to choose.

Very nice to receive your inquiry. Sorry, as the CSB-XP010150HU series proteins are discontinued, so we recommend another species, the similarity is 100%.
Recombinant Pan troglodytes Hemoglobin subunit beta(HBB)
CSB-YP010150EQV >> Yeast
CSB-EP010150EQV >> E.coli
CSB-BP010150EQV >> Baculovirus
CSB-MP010150EQV >> Mammalian cell
Expression Region: 2-147aa; Full length.
Tag information:EP: N-terminal 6xHis-SUMO-tagged; YP, BP, MP: N-terminal 6xHis-tagged
Sequence:

VHLTPEEKSAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSTPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFATLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPPVQAAYQKVVAGVANALAHKYH

Target Background

Function(From Uniprot)

Involved in oxygen transport from the lung to the various peripheral tissues.

Gene References into Functions

Pan troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia. PMID:23765979
We found no evidence of the major deleterious mutations at HBB in chimpanzees that confer resistance to malaria caused by Plasmodium falciparum nor evidence of long-term balancing selection at these loci. PMID:19631293

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Protein Families

Globin family

Tissue Specificity

Red blood cells.

Database Links

UNIGENE: Ptr.4367

KEGG: ptr:450978

STRING: 9598.ENSPTRP00000005700

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