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Recombinant Pan troglodytes CDK5 regulatory subunit-associated protein 2 (CDK5RAP2), partial

Recombinant Pan troglodytes CDK5 regulatory subunit-associated protein 2 (CDK5RAP2), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Abbreviation

CDK5RAP2

Purity

>85% (SDS-PAGE)

Target Names

CDK5RAP2

Uniprot NO.

Q19UN5

Alternative Names

CDK5RAP2CDK5 regulatory subunit-associated protein 2

Species

Pan troglodytes (Chimpanzee)

Source

Yeast

Expression Region

1-1893

Target Protein Sequence

MMDSVLEEDV TVPGTLSGCS GLVPSVPDDL DGINPNAGLG NGVLPNVSEE TVSPTRARNM KDFENQITEL KKENFNLKLR IYFLEERMQQ EFHGPTEHIY KTNIELKVEV ESLKRELQER EQLLIKASKA VESLAEAGGS EIQRVKEDAR KKVQQVEDLL TKRILLLEKD VTAAQAELEK AFAGTETEKA LRLRLESKLS EMKKMHEGDL AMALVLDEKD RLIEELKLSL KSKEALIQCL KEEKSQMASP DENVSSGELR GLCAAPREEK XRETEAAQME HQKERNSFEE RIQALEEDLR EKEREIATEK KNSLKRDKAI QGLTMALKSK EKXVEELNSE IEKLXAAFAK AREALQKAQT QEFQGSEDYE TALSGKEALS AALRSQNLTK STENHRLRRS IKKITQELSD LQQERERLEK DLEEAHREKS KGDCTIRDLR NEVEKLRNEV NEREKAMENR YKSLLSESNK KLHNQEQVVK HLTESTNQKD VLLQKFNEKD LEVIQQNHYL MAAEDLELRS ESLITEKCSS QQPPGSKTIF SKEKKQSSDY EELIQVLKKE QDIYTHLVKS LQESDSINNL QAELNNIFAL RKQLEQDVLS YQNLRKTLEE QISXIRRREE ESFSLYSDQT SYLSICLEEN NRFQVEHFSQ EELKKKVSDL IQLVKELYTD NQHLKKTIFD LSCMGFQGNG FPDRLASTEQ TELLASKEDE DTIKIGEDDE INFLSDEHLQ QSNEIMKDLS KGGCKNGYLR HTESKISDCD GAHAPGCLEE GAFINLLAPL FNEKATLLLE SRPDLLKVVR ELLLGQLFLT EQEVSGEHLD GKTEKTPKQK GELVHFVQTN SFSKPHDELK LSCEAQLVKA GEVPKVGLKD ASVQTVATEG DLLRFKHEAT REAWEEKPIN TALSAEHRPE NLHGVPGWQA ALLSLPGVTN REAKKSRLPI LIKPSRSLGN MYRLPATQEV VTQLQSQILE LQGELKEFKT CNKQLHQKLI LAEAVMEGRP TPDKTLLNAQ PPVGAAYQDS PGEQKGIKTT SSVWRDKEMD SDQQTSYEID SEICPPDDLA SLPSCKENPE DVLSPTSVAT YLSSKSQPSA KVSVMGTDQS ESINTSNETE YLKQKIHDLE TELEAYQNFI FQLQKHSQCS EAIITVLCGT EGAQDGLSKP KSGSDGEEMT FSSLHQVRYV KHVKILGPLA PEMIDSRVLE NLKQQLEEQE YKLQKEQNLN MQLFSEIHNL QNKFRDLSPP RYDSLVQSQA RELSLQRQQI KDGHGICVIS RQHMNTMIKA FEELLQASDV DYCVAEGFQE QLNQCAELLE KLEKLFLNGK SVGVEMNTQI ELMERIEEDN LTYQHLLPES PEPSASHALS DYETSEKSFF SQDQKQDNET EKTSVMVNNF SQDLLMEHIQ EIRTLRKRLE ESIKTNEKLR KQLERQGSEF DQGSTNIFAS GSELHSSLTS EIHFLRKQNQ ALNAMLIKGS RDKQKENDKL RESLSRKTVS LEHLQREYAS VKEENERLQK EGSEKERHNQ QLIQEVRCSG QELSRVQEEV KLRQQLLSQN DKLLQSLRVE LKAYEKLDEE HRRLREASGE GWKGQDPFRD LHSLLMEIQA LRLQLERSIE TSSTLQGRLE EQLARGAEKA QEGALTLAVQ AVSIPEVPLQ LDKHDGDKYP MESDNSFDLF DSSQAVTPKS VSETPPLSGN DTDSLSCDSG SSATSTPCVS RLVTGHHLWA SKNGRHVLGL IEDYEALLKQ ISQGQRLLAE MDVQTQEAPS STSQELGTKG PHPAPLSKFV SSVSTAKLTL EEAYRRLKLL WRVSLPEDGQ CPLHCEQIGE MKAEVTKLHK KLFEQEKKLQ NTMKLLQLSK RQEKVIFDQL VVTHKILRKA RGNLELRPGG SHPGTCSPSR PGS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation. Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of the gamma-tubulin ring complex (gamma-TuRC) onto centrosomes. In complex with PDE4DIP, MAPRE1 and AKAP9, contributes to microtubules nucleation and extension from the centrosome to the cell periphery. Required for the recruitment of AKAP9 to centrosomes. Plays a role in neurogenesis.

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton.

Database Links

UNIGENE: Ptr.6343

KEGG: ptr:464695

STRING: 9598.ENSPTRP00000054333

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