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Recombinant Oncorhynchus mykiss Estrogen receptor (esr1), partial

Recombinant Oncorhynchus mykiss Estrogen receptor (esr1), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

esr1

Uniprot NO.

P16058

Alternative Names

esr1; esr; nr3a1Estrogen receptor; ER; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1

Species

Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)

Source

Yeast

Expression Region

1-622

Target Protein Sequence

MLVRQSHTQI SKPLGAPLRS RTTLESHVIS PPKLSPQQPT TPNSNMYPEE TRGGGGAAAF NYLDGGYDYT APAQGPAPLY YSTTPQDAHG PPSDGSMQSL GSSPTGPLVF VSSSPQLSPQ LSPFLHPPSH HGLPSQSYYL ETSSTPLYRS SVVTNQLSAS EEKLCIASDR QQSYSAAGSG VRVFEMANET RYCAVCSDFA SGYHYGVWSC EGCKAFFKRS IQGHNDYMCP ATNQCTMDRN RRKSCQACRL RKCYEVGMVK GGLRKDRGGR VLRKDKRYCG PAGDREKPYG DLEHRTAPPQ DGGRNSSSSL NGGGGWRGPR ITMPPEQVLF LLQGAEPPAL CSRQKVARPY TEVTMMTLLT SMADKELVHM IAWAKKVPGF QELSLHDQVQ LLESSWLEVL MIGLIWRSIH CPGKLIFAQD LILDRSEGDC VEGMAEIFDM LLATVSRFRM LKLKPEEFVC LKAIILLNSG AFSFCSNSVE SLHNSSAVES MLDNITDALI HHISHSGASV QQQPRRQAQL LLLLSHIRHM SNKGMEHLYS IKCKNKVPLY DLLLEMLDGH RLQSPGKVAQ AGEQTEGPST TTTTSTGSSI GPMRGSQDTH IRSPGSGVLQ YGSPSSDQMP IP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

Gene References into Functions

This study investigetes the functional properties and subcellular localization of alpha human and rainbow trout estrogen receptors. PMID:25595040
The ERalpha1 sequence was the longest and the only one of the four ER isoforms that contained multiple copies of the canonical AU-rich elements (AUUUA) as well as the stability sequence (GCUGAU). PMID:20438355

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Subcellular Location

Nucleus.

Protein Families

Nuclear hormone receptor family, NR3 subfamily

Database Links

UNIGENE: Omy.11637

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