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Recombinant Notophthalmus viridescens Retinoic acid receptor alpha (RARA)

Recombinant Notophthalmus viridescens Retinoic acid receptor alpha (RARA)

Code
MSDS	MSDS Datasheet
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Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

RARA

Uniprot NO.

P18514

Alternative Names

RARA; NR1B1; Retinoic acid receptor alpha; RAR-alpha; Nuclear receptor subfamily 1 group B member 1

Species

Notophthalmus viridescens (Eastern newt) (Triturus viridescens)

Source

Yeast

Expression Region

1-458

Target Protein Sequence

MASNGGSCPS SGGHMNGYPV PHYAFFFPHM LGGLSPPGSL AGIPHPLPVS AYSTPSPATI ETQSTSSEEI VPSPPSPPPL PRIYKPCFVC QDKSSGYHYG VSACEGCKGF FRRSIQKNMV YTCHRDKTCI INKVTRNRCQ YCRLQKCFEV GMSKESVRND RNKKKKQEAP KQECTESYII TPEVEDLVEK VRKAHQETFP ALCQLGKYTT NNSSEERVSL DIDLWDKFSE LSTKCIIKTV EFAKQLPGFT TLTIADQITL LKAACLDILI LRICTRYTPD QDTMTFSDGL TLNRTQMHNA GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDKVDK LQEPLLEALK IYVRKRRPNK PHMFPKMLMK ITDLRSISAK GAERVITLKM EIPGSMPPLI QEMLENSEGL DSLTGQPPRA SSLAPPPGSC SPSLSPSSNR SSPTSHSP
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

full length protein

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

Store at -20°C, for extended storage, conserve at -20°C or -80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. Retinoic acid signaling appears to be involved in specifying proximal-distal axis in limb regeneration.

Subcellular Location

Nucleus.

Protein Families

Nuclear hormone receptor family, NR1 subfamily

Tissue Specificity

Expressed in forelimb, in the distal forelimb blastema, kidney, liver and hindlimb blastemal mesenchymal cells.

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