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Recombinant Neosartorya fumigata Extracellular metalloproteinase mep (mep)

Recombinant Neosartorya fumigata Extracellular metalloproteinase mep (mep)

Baculovirus
Mammalian cell

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
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Product Details
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Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

mep

Uniprot NO.

P46075

Alternative Names

mep; AFUA_8G07080Extracellular metalloproteinase mep; EC 3.4.24.-; Elastinolytic metalloproteinase mep; Fungalysin mep

Species

Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)

Source

Yeast

Expression Region

246-634

Target Protein Sequence

ADYQV YAWGINDPTE GERTVIKDPW DSVASEFTWI SDGSTNYTTS RGNNGIAQSN PSGGSSYLNN YRPSSSSLSF KYPYSVSSSP PSSYIDASII QLFYTANIYH DLLYTLGFTE KAGNFEYNTN GQGGLGNDYV ILNAQDGSGT NNANFATPPD GQPGRMRMYV WTESTPYRDG SFEAGIVIHE YTHGLSNRLT GGPANSNCLN ALESGGMGEG WSDFMATAIR LKPGDKRSTD YTMGEWASNR AGGIRQYPYS TSLSTNPLTY TSVNSLNAVH AIGTVWASML YEVLWNLIDK HGKNDAPKPT LRDGVPTDGK YLAMKLVMDG MALQPCNPNF VQARDAILDA DTALTGGENQ CEIWTAFAKR GLGAGAKYSS RNRVGSTEVP SGVC
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.

Protein Length

Extracellular domain

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

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Target Background

Function(From Uniprot)

Secreted metalloproteinase that allows assimilation of proteinaceous substrates and probably acts as a virulence factor. Catalyzes the hydrolysis of elastin. Hydrolyzes azocasein, synthetic fluorigenic substrate Abz-Ala-Ala-Phe-Phe-pNA, and His-Leu, Ala-Leu, Tyr-Leu, Gly-Phe, and Phe-Phe peptide bonds in the B chain of insulin.

Gene References into Functions

The crystal structure of the archetype of the fungalysin family, Aspergillus fumigatus metalloprotease (AfuMep), has been obtained for the first time. PMID:24100314

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Subcellular Location

Secreted.

Protein Families

Peptidase M36 family

Database Links

KEGG: afm:AFUA_8G07080

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