Home
Product
Protein
Recombinant Proteins
Recombinant Mouse Vesicle-associated membrane protein-associated protein A (Vapa), partial

Recombinant Mouse Vesicle-associated membrane protein-associated protein A (Vapa), partial

Code
MSDS	MSDS Datasheet
Size	Pls inquire
Source
Conjugate
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Abbreviation

Vapa

Purity

>85% (SDS-PAGE)

Target Names

Vapa

Uniprot NO.

Q9WV55

Alternative Names

Vapa; Vap33; Vesicle-associated membrane protein-associated protein A; VAMP-A; VAMP-associated protein A; VAP-A; 33 kDa VAMP-associated protein; VAP-33

Species

Mus musculus (Mouse)

Source

Yeast

Protein Length

Partial

Tag Info

N-terminal His-tagged/Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Storage Condition

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Customer Reviews and Q&A

■ Customer Reviews

Submit a Review here

Target Background

Function(From Uniprot)

Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking.

Gene References into Functions

VAP-33 expression in dendritic cell sarcoma was related to vesicle transportation during antigen processing in dendritic cells. PMID:20021965
These data suggest that VAPA could be involved in prestin's transportation inside outer hair cells (OHCs) and may facilitate the targeting of this abundant OHC protein to the plasma membrane. PMID:20359505
Vapa regulates partitioning of Osbp between the endoplasmic retiuculum and the Golgi apparatus. PMID:15212954

Hide All

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cell membrane; Single-pass type IV membrane protein. Cell junction, tight junction. Nucleus membrane.

Protein Families

VAMP-associated protein (VAP) (TC 9.B.17) family

Tissue Specificity

Ubiquitous.

Database Links

UNIGENE: Mm.266767

KEGG: mmu:30960

STRING: 10090.ENSMUSP00000024897

Promotions